Vetenskapliga publikationer

Här listas några exempel på nyligen publicerade vetenskapliga artiklar från olika forskningsområden inom barncancer. Minst en av författarna till varje artikel har angett att de har finansiellt stöd från Barncancerfonden.

Om du vill synliggöra dina nya forskningsresultat, vänligen kontakta: forskningskommunikation@barncancerfonden.se

Publikationer

Treatment-Related Risk Factors for Diabetes Mellitus in Childhood Cancer Survivors-A Case-Cohort Study Within Adult Life After Childhood Cancer in Scandinavia (ALiCCS).

Kenborg L, Asdahl PH, Bhatia S, Christensen J, Gudmundsdottir T, Hjorth L, Howell R, Krøyer A, Jørgensen M, Laursen MRT, Lassen-Ramshad Y, de Fine Licht S, Nielsen TT, Rechnitzer C, Smith SA, Wiebe T, Hasle H, Holmqvist AS; ALiCCS study group.Pediatr Blood Cancer. 2025 May 21:e31805. doi: 10.1002/pbc.31805. Online ahead of print.PMID: 40399750

Sulforaphane promotes natural killer cell-mediated anti-tumor immune responses partially via cGAS-STING pathway in classical Hodgkin lymphoma.

Xagoraris I, Yang Y, Bougka E, Trogrlic D, Xyderou P, Stathopoulou K, Herold N, Lundqvist A, Rassidakis GZ.Leukemia. 2025 Apr 28. doi: 10.1038/s41375-025-02627-1. Online ahead of print.PMID: 40295827 No abstract available.

Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth.

Treis D, Lundberg KI, Bell N, Polychronopoulos PA, Tümmler C, Åkerlund E, Aliverti S, Lilienthal I, Pepich A, Seashore-Ludlow B, Sakaguchi K, Kogner P, Johnsen JI, Wickström M.Cell Death Dis. 2025 Apr 19;16(1):318. doi: 10.1038/s41419-025-07658-1.PMID: 40253363 Free PMC article.

Voices of Children with Cancer and Their Siblings in the Family Talk Intervention.

Ayoub M, Lövgren M, Kreicbergs U, Udo C.Children (Basel). 2025 Feb 21;12(3):266. doi: 10.3390/children12030266.PMID: 40150549 Free PMC article.

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma.

Ohata Y, Ali MM, Tsubakihara Y, Itoh Y, Rosén G, Bergström T, Morén A, Golán-Cancela I, Nakada A, Voytyuk O, Tsuchiya M, Fukui R, Yamamoto K, Martín-Rubio P, Sancho P, Strell C, Micke P, Wechsler-Reya RJ, Hashizume Y, Miyazono K, Caja L, Heldin CH, Swartling FJ, Moustakas A.Cell Death Differ. 2025 Mar 28. doi: 10.1038/s41418-025-01488-6. Online ahead of print.PMID: 40148468

Discovery of Cis-Regulatory Mechanisms via Non-Coding Mutations in Acute Lymphoblastic Leukemia.

Aydın E, Woodward EL, Dushime GT, Gunnarsson R, Lilljebjörn H, Moura-Castro LH, Fioretos T, Johansson B, Paulsson K, Yang M.Genes Chromosomes Cancer. 2025 Mar;64(3):e70045. doi: 10.1002/gcc.70045.PMID: 40145864 Free PMC article.

The proto-oncogenic miR-106a-363 cluster enhances adverse risk acute myeloid leukemia through mitochondrial activation.

Sperb N, Maksakova IA, Escano L, Abraham L, MacPhee L, Cabantog A, Kim D, Yu M, Krowiorz K, Im J, Grasedieck S, Pochert N, Ruess C, Rösler R, Flibotte S, Maetzig T, Calzia E, Palmqvist L, Wiese S, Fogelstrand L, Gold MR, Rouhi A, Kuchenbauer F.Leukemia. 2025 May;39(5):1090-1101. doi: 10.1038/s41375-025-02558-x. Epub 2025 Mar 17.PMID: 40097604

Nelarabine in T-cell acute lymphoblastic leukemia: intracellular metabolism and molecular mode-of-action.

Hormann FM, Rudd SG.Leukemia. 2025 Mar;39(3):531-542. doi: 10.1038/s41375-025-02529-2. Epub 2025 Feb 17.PMID: 39962329 Free PMC article. Review.

Validity and reliability of the Swedish version of the Visual CARE Measure for assessing children's perceptions of nurses' empathy.

Wiljén A, Chaplin J, Nilsson S, Karlsson K, Öhlén J, Schwarz A.Eur J Pediatr. 2025 Jan 18;184(2):145. doi: 10.1007/s00431-025-05979-z.PMID: 39827260 Free PMC article.

Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State.

Embaie BT, Sarkar H, Alchahin AM, Otte J, Olsen TK, Tümmler C, Kameneva P, Artemov AV, Akkuratova N, Adameyko I, Stukenborg JB, Wickström M, Kogner P, Johnsen JI, Mei S, Kharchenko PV, Baryawno N.Cancer Res. 2025 Mar 14;85(6):1015-1034. doi: 10.1158/0008-5472.CAN-24-1507.PMID: 39808065 Free PMC article.

Characterisation of heritable TP53-related cancer syndrome in Sweden-a nationwide study of genotype-phenotype correlations in 90 families.

Omran M, Liu Y, Sun Zhang A, Poluha A, Stenmark-Askmalm M, Persson F, Hallbeck AL, Rosén A, Helgadottir HT, Tham E, Bajalica-Lagercrantz S.Eur J Hum Genet. 2025 Apr;33(4):513-522. doi: 10.1038/s41431-024-01753-1. Epub 2025 Jan 5.PMID: 39757328 Free PMC article.

Influence of therapy exposures on specific late morbidities, prescription drug purchases, and mortality in aging male survivors of childhood cancer: A registry-based study.

Koskela M, Korhonen M, Haavisto A, Jahnukainen K.Int J Cancer. 2025 Mar 15;156(6):1236-1246. doi: 10.1002/ijc.35247. Epub 2024 Nov 4.PMID: 39497230 Free PMC article.

Longitudinal trends in testicular volume z scores from puberty to adulthood, sperm quality, and paternity outcomes after childhood cancer.

Korhonen M, Jahnukainen K, Koskela M.Cancer. 2025 Jan 1;131(1):e35623. doi: 10.1002/cncr.35623. Epub 2024 Oct 29.PMID: 39470456 Free PMC article.

Educational outcomes school year nine in children treated for acute lymphoblastic leukemia: A nationwide registry-based study from Sweden.

Zhou O, Harila A, Hovén E, Lönnerblad M.Int J Cancer. 2025 Apr 1;156(7):1347-1357. doi: 10.1002/ijc.35231. Epub 2024 Oct 19.PMID: 39425561 Free PMC article.

Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.

van Bree N, Oppelt AS, Lindström S, Zhou L, Boutin L, Coyle B, Swartling FJ, Johnsen JI, Bräutigam L, Wilhelm M.Neuro Oncol. 2025 Mar 7;27(3):779-794. doi: 10.1093/neuonc/noae210.PMID: 39383211 Free PMC article.

Psychiatric disorders among survivors of childhood acute lymphoblastic leukemia in Denmark and Sweden.

Sørensen GV, Mogensen H, Holmqvist AS, Kenborg L, Pedersen C, Nielsen TT, Talbäck M, Erdmann F, Ifversen M, Feychting M, Schmiegelow K, Heyman MM, Winther JF, Hasle H, Frederiksen LE.Pediatr Blood Cancer. 2024 Dec;71(12):e31361. doi: 10.1002/pbc.31361. Epub 2024 Oct 7.PMID: 39375822

A pilocytic astrocytoma with novel ATG16L1::NTRK2 fusion responsive to larotrectinib: a case report with genomic and functional analysis.

Deland L, Keane S, Olsson Bontell T, Sjöberg Bexelius T, Gudinaviciene I, De La Cuesta E, De Luca F, Nilsson JA, Carén H, Mörse H, Abel F.Oncologist. 2025 Mar 10;30(3):oyae254. doi: 10.1093/oncolo/oyae254.PMID: 39326005 Free PMC article.

Haemostasis during early treatment of childhood acute lymphoblastic leukaemia with the ALLTogether protocol.

Fermér J, Jalnäs J, Abrahamsson J, Borssen M, Donnér I, Henriksson L, Heyman M, Holmqvist AS, Valind A, Vogt H, Wretman A, Zhou O, Harila A, Ranta S.Acta Paediatr. 2024 Dec;113(12):2676-2678. doi: 10.1111/apa.17398. Epub 2024 Aug 27.PMID: 39190328 Free article. No abstract available.

Defining neuroblastoma: From origin to precision medicine.

Sainero-Alcolado L, Sjöberg Bexelius T, Santopolo G, Yuan Y, Liaño-Pons J, Arsenian-Henriksson M.Neuro Oncol. 2024 Dec 5;26(12):2174-2192. doi: 10.1093/neuonc/noae152.PMID: 39101440 Free PMC article. Review.

Occurrence of cancer in Marfan syndrome: Report of two patients with neuroblastoma and review of the literature.

Maya-González C, Delgado-Vega AM, Taylan F, Lagerstedt Robinson K, Hansson L, Pal N, Fagman H, Puls F, Wessman S, Stenman J, Georgantzi K, Fransson S, Díaz De Ståhl T, Ek T, Palmer R, Tesi B, Kogner P, Martinsson T, Nordgren A.Am J Med Genet A. 2024 Dec;194(12):e63812. doi: 10.1002/ajmg.a.63812. Epub 2024 Jul 11.PMID: 38990105 Review.

 

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